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1.
Oper Orthop Traumatol ; 34(2): 90-97, 2022 Apr.
Artigo em Alemão | MEDLINE | ID: mdl-34739548

RESUMO

OBJECTIVE: Treatment of non-responding pain to conservative treatment located at the anterolateral thigh with surgical decompression of the lateral femoral cutaneous nerve of the thigh (LFCN). INDICATIONS: Compression syndrome of the LFCN; patients suffering from the following symptoms: pain (dysesthesia), numbness (paresthesia), hypersensibility to temperature (or temperature changes) along the course of the LFCN located at the anterolateral thigh. CONTRAINDICATIONS: A new or recrudescent hernia with additional pain or recent laparoscopic hernia repair as a supposed iatrogenically induced compression of the LFCN. SURGICAL TECHNIQUE: Dissection and release of the LFCN of connective tissue, scar tissue, bone rims, and retraction located along the passage underneath the inguinal ligament and distally. POSTOPERATIVE MANAGEMENT: Suture removal after 10-14 days, no sports for 2 weeks. Physiotherapy if necessary. Neurography 4 months after surgery (obligatory if symptoms are persistent). The patient should be followed up for about 24 months. RESULTS: Of the patients, 69% had a history of trauma or surgery, which were designated as the onset of pain. Of these patients, 78% had hip prostheses and 22% had previous falls. Postoperatively, a significant reduction of pain of 6.6 points on the numeric rating scale was observed. All other evaluated parameters also improved postoperatively. Patient satisfaction was high, with 86% reporting complete satisfaction, and 14% reporting partial satisfaction.


Assuntos
Neuropatia Femoral , Síndromes de Compressão Nervosa , Descompressão , Neuropatia Femoral/diagnóstico , Neuropatia Femoral/cirurgia , Humanos , Síndromes de Compressão Nervosa/diagnóstico , Síndromes de Compressão Nervosa/cirurgia , Coxa da Perna/cirurgia , Resultado do Tratamento
2.
Ann Med Surg (Lond) ; 69: 102662, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-34429947

RESUMO

INTRODUCTION: Traumatic peroneal nerve injury (PNI) caused by ski or snowboard edges is a severe but scarcely reported accident. METHODS: In a 20-year retrospective study, all skiers and snowboarders with this injury treated surgically at the Department of Plastic, Reconstructive and Aesthetic Surgery at the Medical University of Innsbruck, Austria, were included, covering a period from 1999/2000 to 2018/2019. RESULTS: In total, 34 patients were included in this study (30 males (88.2%) and 4 (11.8%) females). Of these 34 injured skiers or snowboarders, 33 (97.1%) were recreational athletes and Non-Austrian citizens, and 21 (61.8%) patients sustained accidental injuries without collision. All of the injuries under investigation, i.e., open lacerations, most often with complete transection, were the patients' main injuries. Surgery was performed with direct coaptation in 24 patients (70.6%), and with a suralis nerve graft in the other 10 patients (29.4%). CONCLUSION: Traumatic laceration of the peroneal nerve at the knee level by sharp ski or snowboard edges is a rare but severe injury. Causes for this injury may be multifactorial. Recommendations to reduce the risk of such an injury may follow general instructions and warnings to skiers and snowboarders regarding equipment, familiarity with the region, as well as appropriate skills and training.

3.
Oper Orthop Traumatol ; 32(5): 467-474, 2020 Oct.
Artigo em Alemão | MEDLINE | ID: mdl-32100068

RESUMO

OBJECTIVE: Functional and sensible regeneration of deficits related to common peroneal nerve palsy. INDICATIONS: Functional deficits like foot drop, malfunctioning pronation, foot in supination and sensible deficits located at the anterior and lateral lower leg, the dorsum of the foot, the extension side of toes 1-4 and the interdigital space between toe 1 and 2, for positive Hoffmann-Tinel sign located at the fibular head and steppage gait. CONTRAINDICATIONS: Infection, spinal cord damage and spinal cord tumors with related sensitivity disorders and paralysis, advanced multiple sclerosis, amyotrophic lateral sclerosis, pAVK IV, reinnervation refractory muscles with denervation >15-18 months, polyneuropathy, previous nerve lesions by direct trauma. SURGICAL TECHNIQUE: Surgery in lateral position and thigh tourniquet. L­Shaped incision made in accordance with the marking. Nerve release by fasciotomy first proximal, then distal up to the branching. Opening of the thigh tourniquet, careful coagulation. Insertion of a Mini Redovac Drainage, subcutaneous and skin sutures. Compression bandage. POSTOPERATIVE MANAGEMENT: Full mobilization on postoperative day 1. An electric stimulation therapy can be considered after drainage removal. After suture removal physio- and ergotherapy indicated. Check ups should be performed every 3 months with clinical exams, photo and video documentation. Four months after surgery an electroneurographic exam should be done. Follow-up should be performed for 24 months. RESULTS: From 2010-2018 15 patients received decompression of the common peroneal nerve. Sensibility, functionality and subjective feeling were evaluated. In 12 patients (80%) a full recovery, in one case (6.67%) a partial recovery and in 2 cases (13.33%) no recovery was observed.


Assuntos
Nervo Fibular , Descompressão Cirúrgica , Fíbula/diagnóstico por imagem , Fíbula/cirurgia , Humanos , Nervo Fibular/cirurgia , Neuropatias Fibulares/diagnóstico , Neuropatias Fibulares/cirurgia , Resultado do Tratamento
4.
Eur Surg ; 48: 129-133, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27398082

RESUMO

BACKGROUND: Anatomical variance of the deep circumflex iliac artery is of high clinical value in facial reconstruction using a deep circumflex iliac artery perforator (DCIAP) flap. METHODS: We present the case of a 76-year-old woman treated with an osteomyocutaneous DCIAP flap variant for facial reconstruction. We also review here the literature on DCIA perforator flaps and the different anatomical variances, which might bring clinical benefits. RESULTS: The observed anatomy in our patient offered the possibility to raise a free flap variant with high mobility of a large skin paddle and a long vascular pedicle combined with a variable osteomuscular portion. CONCLUSION: The characteristics of the flap thus raised help overcome the disadvantages of the conventional DCIAP flap and offer excellent options for facial reconstruction.

6.
Chirurg ; 86(5): 476-81, 2015 May.
Artigo em Alemão | MEDLINE | ID: mdl-24969345

RESUMO

BACKGROUND: Autologous fat has many qualities for an ideal filler and is widely used in reconstructive and aesthetic surgery, especially in the treatment of primary and secondary deformities of the breast. METHODS: From May 2007 to September 2012 298 autologous fat graftings were performed in 199 patients. Fat was harvested using the Tissue-Trans™ (Shippert Medical), Lipivage™ (Polytech) or a self-developed harvesting system and injected without any further processing into subcutaneous and/or intramuscular layers. RESULTS: The mean patient age was 45 years. Main indications were contour deformities and volume loss after breast cancer surgery as well as asymmetry, hypoplasia, Poland syndrome or tuberous breasts. The average volume of grafted fat was 90 ml per surgery. Most patients received one (42 %) or two (31 %) sessions of treatment. The infection rate was 2 % which was further treated with oral antibiotics. CONCLUSION: Autologous fat grafting represents an important tool for the management of deformities of the breast not only by filling deformities and adding volume, but also by improving the quality of scars. It is a simple, fast and effective treatment option with few complications.


Assuntos
Tecido Adiposo/transplante , Neoplasias da Mama/cirurgia , Mamoplastia/métodos , Adolescente , Adulto , Idoso , Estética , Feminino , Humanos , Injeções Intramusculares , Injeções Subcutâneas , Mamoplastia/instrumentação , Pessoa de Meia-Idade , Estudos Retrospectivos , Instrumentos Cirúrgicos , Coleta de Tecidos e Órgãos/instrumentação , Coleta de Tecidos e Órgãos/métodos , Adulto Jovem
7.
Handchir Mikrochir Plast Chir ; 45(6): 344-9, 2013 Dec.
Artigo em Alemão | MEDLINE | ID: mdl-24357479
8.
Oper Orthop Traumatol ; 25(2): 176-84, 2013 Apr.
Artigo em Alemão | MEDLINE | ID: mdl-23512178

RESUMO

OBJECTIVE: Stable soft tissue coverage of exposed bone, tendons, or hardware in the extremities or the head and neck area with a microsurgically grafted free flap. INDICATIONS: Soft tissue defects measuring up to 42 × 15 cm in the extremities and the head and neck region. CONTRAINDICATIONS: Previous surgery or trauma in the anterolateral thigh region. Insufficient personnel and/or technical resources. SURGICAL TECHNIQUE: A line is marked from the anterior superior iliac spine to the superolateral patella pole, approaching the intermuscular septum between the rectus femoris and vastus lateralis muscle. The flap is centred on this line and after medial incision the perforators of the descending branch of the lateral circumflex femoral artery are identified and dissected to their origin. Afterwards the lateral incision is carried out and flap dissection is completed. After flap transfer microsurgical anastomoses are performed and the flap is sutured to the recipient region. POSTOPERATIVE MANAGEMENT: Flap monitoring for 1 week. Strict elevation and immobilization after flap transfer to the extremities; bedrest for 1 week. Thrombosis prophylaxis. RESULTS: From 2008-2011, 41 free anterolateral thigh flaps in 5 women and 36 men with an average age of 53 years (38-70 years) were performed for microsurgical soft tissue reconstruction. Total flap loss rate was 2.4 % and reoperation due to complications, e.g., hematoma, problems with microsurgical anastomosis, and partial flap loss was necessary in 13.8 % of patients.


Assuntos
Traumatismos do Braço/cirurgia , Traumatismos Craniocerebrais/cirurgia , Retalhos de Tecido Biológico/transplante , Traumatismos da Perna/cirurgia , Lesões do Pescoço/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Lesões dos Tecidos Moles/cirurgia , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Procedimentos de Cirurgia Plástica/instrumentação , Coxa da Perna/cirurgia , Resultado do Tratamento
9.
Chirurg ; 82(9): 820, 822-7, 2011 Sep.
Artigo em Alemão | MEDLINE | ID: mdl-21678104

RESUMO

The anterolateral thigh flap (ATL) has become a standard procedure in reconstructive microsurgery. In this study the results with the ALT for reconstruction in the head and neck area after tumor resection in 33 patients were retrospectively analyzed. Patients included 28 men and 5 women aged 47-70 years who suffered from intraoral and extraoral tumors. Satisfactory soft tissue coverage could be achieved in all patients and no flaps were lost. The ALT is a versatile free flap enabling reliable soft tissue reconstruction of complex defects in the head and neck region. Flap dissection and preparation of the recipient area can usually be performed simultaneously. Additional advantages include the long and strong caliber vascular pedicle, the low donor site morbidity and the different possibilities of tissue composition, making the ALT a workhorse flap in modern reconstructive microsurgery.


Assuntos
Adenocarcinoma/cirurgia , Adenoma Pleomorfo/cirurgia , Carcinoma de Células Escamosas/cirurgia , Retalhos de Tecido Biológico/irrigação sanguínea , Microcirurgia/métodos , Neoplasias Otorrinolaringológicas/cirurgia , Adulto , Idoso , Anastomose Cirúrgica/métodos , Artérias/cirurgia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Bucais/cirurgia , Neoplasias Orofaríngeas/cirurgia , Neoplasias Otorrinolaringológicas/radioterapia , Neoplasias dos Seios Paranasais/cirurgia , Complicações Pós-Operatórias/cirurgia , Radioterapia Adjuvante , Reoperação , Estudos Retrospectivos , Coleta de Tecidos e Órgãos/métodos , Veias/cirurgia
10.
Handchir Mikrochir Plast Chir ; 41(4): 210-6, 2009 Aug.
Artigo em Alemão | MEDLINE | ID: mdl-19688651

RESUMO

In the 20th century the legend of Cosmas and Damian - an extremity being transferred from one person to another - became reality. The first hand transplantation was carried out in 1964 in Ecuador but the hand had to be removed again within three weeks due to rejection. Although he was the first one to be treated with more modern immunosuppressants, the same fate overtook another patient who received a hand from a brain-dead donor in 1998 in Lyon. Since then only 32 persons worldwide have been provided with parts of the upper extremity. The partly published histories of three patients who have had both hands transplanted will be summarised and indication critically assessed once again. It is also stressed how difficult, multi-layered and complex the patient's education is. The patient has to be informed in many conversations beforehand about every stage of therapy but also about possible complications and even rejection. Can the psychological burden/stress while waiting for a donor, the difficult post-operative period, lifelong adherence to a rigorous drug-regimen, the complexity of the whole procedure be made comprehensible to a layman? To replace same with same is the goal of the best-possible reconstructive surgery. It is to hope that through future innovations in the immunosuppressing therapy patients can be offered transplantation of one or both hands as a routine-operation. Until then indication has to be strict and the operation can possibly only be performed in a few centres. Long-time prospects, disadvantages and complications, as well as side effects have to be presented openly.


Assuntos
Amputação Traumática/cirurgia , Traumatismos do Antebraço/cirurgia , Traumatismos da Mão/cirurgia , Transplante de Mão , Microcirurgia/métodos , Retalhos Cirúrgicos , Adulto , Traumatismos por Explosões/cirurgia , Traumatismos por Eletricidade/cirurgia , Seguimentos , Rejeição de Enxerto/tratamento farmacológico , Rejeição de Enxerto/etiologia , Rejeição de Enxerto/prevenção & controle , Força da Mão/fisiologia , Hospitais Universitários , Humanos , Imunossupressores/uso terapêutico , Masculino , Pessoa de Meia-Idade , Destreza Motora/fisiologia , Educação de Pacientes como Assunto/métodos , Satisfação do Paciente , Assistência Perioperatória/métodos , Força de Pinça/fisiologia , Complicações Pós-Operatórias/tratamento farmacológico , Complicações Pós-Operatórias/fisiopatologia , Amplitude de Movimento Articular/fisiologia , Retalhos Cirúrgicos/irrigação sanguínea , Retalhos Cirúrgicos/inervação , Doadores de Tecidos , Adulto Jovem
11.
Eur J Pediatr Surg ; 18(5): 347-9, 2008 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-18924071

RESUMO

We report on a four-year-old girl who suffered a complex mincer injury to the left hand, resulting in a partial amputation of her hand. To salvage the injured hand, revascularization was performed. The indication, advantages and outcome of the procedure are discussed.


Assuntos
Falanges dos Dedos da Mão/irrigação sanguínea , Traumatismos da Mão/cirurgia , Traumatismo Múltiplo , Reimplante/métodos , Pré-Escolar , Feminino , Falanges dos Dedos da Mão/fisiopatologia , Seguimentos , Fixação de Fratura/métodos , Humanos , Amplitude de Movimento Articular
12.
Unfallchirurg ; 111(1): 5-11, 2008 Jan.
Artigo em Alemão | MEDLINE | ID: mdl-18210032

RESUMO

BACKGROUND: Large complex soft-tissue defects on the dorsum of the foot, with exposed tendons, joints, bones, nerves and vessels, have to be reconstructed by transplantation of free tissue grafts with good blood flow. PATIENTS AND METHODS: Evaluation of 19 patients with an average age of 38 years who underwent closure of defects on the dorsum of the foot with free muscle flaps (with split-thickness skin grafts) in 14 cases and with free fasciocutaneous flaps in 5 is presented. In 10 patients a gracilis muscle flap was used, in 4 patients a latissimus dorsi flap, and in 2 patients a groin flap, while in 1 patient each an anterolateral thigh flap, an anteromedial thigh flap and a lateral arm flap was used. The aesthetic outcome was evaluated with reference to skin texture, pigmentation, thickness of the free flap and scar formation. The Stanmore system was used to determine the postoperative functional results. RESULTS: On average, patients were followed up for 29 months. We had no flap loss. A flap debulking procedure was performed in 6 patients. Better aesthetic results were obtained with muscle flaps plus skin graft than with fasciocutaneous flaps. Functional results were excellent in 6 patients, good in 5 and poor in 8 patients. CONCLUSION: Free muscle flaps with skin grafts, particularly the free gracilis muscle flap, are superior to fasciocutaneous flaps and perforating flaps in aesthetic outcome and donor site morbidity.


Assuntos
Traumatismos do Pé/cirurgia , Pé/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Recuperação de Função Fisiológica , Lesões dos Tecidos Moles/cirurgia , Retalhos Cirúrgicos , Adulto , Estética , Feminino , Traumatismos do Pé/diagnóstico , Humanos , Masculino , Lesões dos Tecidos Moles/diagnóstico , Resultado do Tratamento
13.
Acta Neurochir Suppl ; 100: 113-5, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17985558

RESUMO

We studied cortical activation patterns by functional MRI in a patient who received bilateral hand transplantation after amputation 6 years ago. In the early post-operative period, the patient who had had the hand transplantation revealed strong activation of a higher motor area, only weak activation of the primary sensorimotor motor cortex and no activation of the primary somatosensory cortex. At one-year follow-up, a small increase in primary sensorimotor motor cortex activation was observed. Activation of the primary somatosensory cortex was only seen at the 2-year follow-up. Transplantation after long-standing amputation results in cortical reorganisation occurring over a two-year period.


Assuntos
Transplante de Mão , Mãos/fisiopatologia , Córtex Motor/fisiopatologia , Reimplante , Amputação Traumática/cirurgia , Bombas (Dispositivos Explosivos) , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Movimento , Córtex Somatossensorial/fisiopatologia , Fatores de Tempo
14.
Anaesthesia ; 61(10): 959-61, 2006 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-16978311

RESUMO

The purpose of this study was to evaluate touch sensitivity and static two-point discrimination of the dominant index and middle finger in 20 anaesthetists wearing no gloves, single-use protective gloves or sterile standard surgical gloves. Semmes-Weinstein filaments were used to measure cutaneous pressure thresholds, and a Two-Point-Discriminator to estimate static two-point discrimination. Wearing gloves significantly reduced touch sensitivity (p < 0.01), but not two-point discrimination. No difference in touch sensitivity or two-point discrimination was found between different types of gloves. The results of our study suggest that the additional cost of sterile standard surgical gloves can not be justified in terms of touch sensitivity.


Assuntos
Luvas Protetoras , Tato , Anestesiologia/instrumentação , Discriminação Psicológica , Equipamentos Descartáveis , Dedos/fisiologia , Luvas Cirúrgicas , Humanos , Pressão , Limiar Sensorial
15.
J Plast Reconstr Aesthet Surg ; 59(9): 994-8, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-16920595

RESUMO

In March of 2000 and May of 2002, two patients underwent restoration of knee extension with a free neurovascular rectus femoris flap. The female patient was 10 years and the male patient 19 years old. Both patients sustained a complex trauma of the thigh with fracture of the femur and posttraumatic loss of quadriceps femoris muscles. Follow up of the patients was 51 and 27 months. After 8 months reinnervation were detected by Electromyography (EMG) in both patients and contraction became visible 2 months later. The female patient obtained a good and the male patient a very good functional result. Both patients were able to walk unaided. The authors concluded that free functional rectus femoris transfer can obtain excellent results in treating knee extension and soft-tissue defect due to trauma and loss of the quadriceps femoris muscles.


Assuntos
Articulação do Joelho/fisiopatologia , Procedimentos de Cirurgia Plástica/métodos , Músculo Quadríceps/lesões , Músculo Quadríceps/transplante , Adulto , Criança , Eletromiografia , Feminino , Humanos , Masculino , Amplitude de Movimento Articular , Recuperação de Função Fisiológica , Retalhos Cirúrgicos
16.
Handchir Mikrochir Plast Chir ; 38(2): 113-8, 2006 Apr.
Artigo em Alemão | MEDLINE | ID: mdl-16680668

RESUMO

We describe a dramatic case of class II non-Langerhans cell histiocytosis, xanthoma disseminatum, in a 30-year-old male patient with progressive involvement of the skin, vocal cords, eyes, bones and nerves in spite of chemotherapy with Vespesid and immunotherapy with interferon-gamma. At the age of 43 years, the patient required surgical clearance of airways, eyelids and peripheral nerves, but at present exhibits stable disease on a combination of lipid-lowering drugs including thiazolidinedione.


Assuntos
Deformidades Adquiridas da Mão/diagnóstico , Histiocitose de Células não Langerhans/diagnóstico , Síndromes de Compressão do Nervo Ulnar/diagnóstico , Articulação do Punho , Adulto , Obstrução das Vias Respiratórias/diagnóstico , Obstrução das Vias Respiratórias/cirurgia , Terapia Combinada , Doenças da Túnica Conjuntiva/diagnóstico , Doenças da Túnica Conjuntiva/cirurgia , Doenças da Córnea/diagnóstico , Doenças da Córnea/cirurgia , Progressão da Doença , Dermatoses Faciais/diagnóstico , Dermatoses Faciais/cirurgia , Deformidades Adquiridas da Mão/cirurgia , Histiocitose de Células não Langerhans/cirurgia , Humanos , Hipolipemiantes/administração & dosagem , Masculino , Otorrinolaringopatias/diagnóstico , Otorrinolaringopatias/cirurgia , Cuidados Paliativos , Dermatopatias/diagnóstico , Tiazolidinedionas/administração & dosagem , Traqueotomia , Síndromes de Compressão do Nervo Ulnar/cirurgia , Articulação do Punho/cirurgia
17.
J Hand Surg Br ; 30(5): 530-3, 2005 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-16055246

RESUMO

We studied cortical activation patterns by functional MRI in a patient who received bilateral hand transplantation after amputation 6 years ago and in a patient who had received unilateral hand replantation within 2 hours after amputation. In the early postoperative period, the patient who had had the hand transplantation revealed strong activation of a higher motor area, only weak activation of the primary sensorimotor motor cortex and no activation of the primary somatosensory cortex. At 1-year follow-up, a small increase in primary sensorimotor motor cortex activation was observed. Activation of the primary somatosensory cortex was only seen at the 2 year follow-up. By contrast, after hand replantation, the activation pattern was similar to that of the uninjured hand within 6 weeks. This included activation of the primary sensorimotor motor cortex, higher motor areas and primary somatosensory cortex. Transplantation after long-standing amputation results in cortical reorganization occurring over a 2-year period. In contrast, hand replantation within a few hours preserves a normal activation pattern.


Assuntos
Mãos/cirurgia , Córtex Motor/fisiologia , Reimplante , Adulto , Feminino , Mãos/fisiologia , Humanos , Processamento de Imagem Assistida por Computador , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Movimento/fisiologia , Transplante Homólogo
18.
Br J Plast Surg ; 58(2): 175-82, 2005 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-15710112

RESUMO

Donor-site morbidity in four patients after reconstruction with free neurovascular rectus femoris muscle was examined through a series of strength tests in which the leg with rectus femoris muscle harvested was compared with the contralateral leg with an intact rectus femoris muscle. The tests were conducted with three testing devices: (1) the 'Con-Trex Leg-press' in which the force and power of right and left leg extensions at 0.2 and 0.4 m/s in a knee angle from 50 to 90 degrees were tested separately; (2) the isometric power tester, which enabled the unilateral evaluation of the isometric leg extension at three knee angles: 50, 70 and 90 degrees ; and (3) at the 'SP-Force Platforms' in which the patients performed a counter-movement jump where the amplitude of the ground reaction force, the parameters maximum force, and the jump height were calculated in order to compare the right and left leg during a single dynamic movement. Our results showed that the patients (with one exception) demonstrated a balanced relationship between the donor leg and the intact contralateral leg. The patient that primarily demonstrated a large strength deficit was retested 3 months later and showed, after an extensive rehabilitation and training program, an impressive increase in strength. The authors concluded that there is no significant limitation in the strength of the donor leg after removal of the rectus femoris muscle and consequently no significant functional donor-site morbidity. We believe that for the realisation of such results that the intraoperative linking of the vastus lateralis muscle with the vastus medialis muscle, especially in their lower third, and an extensive postoperative rehabilitation and training program are essential.


Assuntos
Doadores Vivos , Músculo Esquelético/transplante , Complicações Pós-Operatórias/etiologia , Retalhos Cirúrgicos , Adolescente , Adulto , Criança , Exercício Físico/fisiologia , Feminino , Humanos , Perna (Membro)/fisiologia , Masculino , Músculo Esquelético/fisiologia , Cuidados Pós-Operatórios/métodos , Complicações Pós-Operatórias/fisiopatologia
19.
Unfallchirurg ; 107(9): 761-8, 2004 Sep.
Artigo em Alemão | MEDLINE | ID: mdl-15502901

RESUMO

The aim of primary treatment for eyebrow injuries should be preservation of the original eyebrow under any circumstances. Debridement should be kept to a minimum even when the wound is severe. The treatment of total or partial loss of an eyebrow concerning the exact reconstruction of details and aesthetic aspects is a challenge for the surgeon. The therapy option depends on the type of eyebrow selected for reconstruction. We present a classification for eyebrow injuries, which considers type and size of defects. Based on this, different techniques and methods of reconstruction are recommended. Advantages and disadvantages are discussed and illustrated by several examples.


Assuntos
Traumatismos Oculares/diagnóstico , Traumatismos Oculares/cirurgia , Sobrancelhas/patologia , Procedimentos de Cirurgia Plástica/métodos , Traumatismos Oculares/classificação , Traumatismos Faciais/classificação , Traumatismos Faciais/diagnóstico , Traumatismos Faciais/cirurgia , Humanos , Guias de Prática Clínica como Assunto , Padrões de Prática Médica
20.
Biomaterials ; 25(9): 1649-55, 2004 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-14697866

RESUMO

Defects caused by traumatic or postsurgical loss of muscle mass may result in severe impairments of the functionality of skeletal muscle. Tissue engineering represents a possible approach to replace the lost or defective muscle. The aim of this study was to compare the suitability of three different biomaterials as scaffolds for rat myoblasts, using a new animal model. PKH26-fluorescent-stained cultured rat myoblasts were either seeded onto polyglycolic acid meshes or, alternatively, suspended in alginate or in hyaluronic acid-hydrogels. In each of the eight Fisher CDF-344 rats, four capsule pouches were induced by subcutaneous implantation of four silicone sheets. After two weeks the silicone sheets were removed and myoblast-biomaterial-constructs were implanted in the preformed capsules. Specimens were harvested after four weeks and examined histologically by H&E-staining and fluorescence microscopy. All capsules were well-vascularized. Implanted myoblasts fused by forming multinucleated myotubes. This study demonstrates that myoblasts seeded onto different biomaterials can be successfully transplanted into preformed highly vascularized capsule pouches. Our animal model has paved the way for studies of myoblast-biomaterial transplantations into an ectopic non-muscular environment.


Assuntos
Implantes Absorvíveis , Reação a Corpo Estranho/patologia , Teste de Materiais/métodos , Mioblastos Esqueléticos/patologia , Mioblastos Esqueléticos/transplante , Engenharia Tecidual/métodos , Animais , Técnicas de Cultura de Células/instrumentação , Técnicas de Cultura de Células/métodos , Divisão Celular , Transplante de Células/efeitos adversos , Transplante de Células/instrumentação , Transplante de Células/métodos , Células Cultivadas , Reação a Corpo Estranho/etiologia , Modelos Animais , Ratos , Ratos Endogâmicos F344 , Engenharia Tecidual/instrumentação
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